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Converting cancer mutations into therapeutic opportunities

While the use of synthetic lethality has been around for decades in model organism studies, it has only recently been applied to cancer therapy and judging by recent results, with great success. Following on a recent paper that demonstrates the clinical application of this strategy (Fong et al, 2009...

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Detalles Bibliográficos
Autores principales: O'Brien, Tom, Stokoe, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378146/
https://www.ncbi.nlm.nih.gov/pubmed/20049732
http://dx.doi.org/10.1002/emmm.200900044