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Neurodegenerative diseases: Lessons from genome-wide screens in small model organisms

Various age-related neurodegenerative diseases, including Parkinson's disease, polyglutamine expansion diseases and Alzheimer's disease, are associated with the accumulation of misfolded proteins in aggregates in the brain. How and why these proteins form aggregates and cause disease is st...

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Detalles Bibliográficos
Autores principales: van Ham, Tjakko J, Breitling, Rainer, Swertz, Morris A, Nollen, Ellen A A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378155/
https://www.ncbi.nlm.nih.gov/pubmed/20049741
http://dx.doi.org/10.1002/emmm.200900051