Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

More than a thousand disease susceptibility loci have been identified via genome-wide association studies (GWAS) of common variants; however, the specific genes and full allelic spectrum of causal variants underlying these findings generally remain to be defined. We utilize pooled next-generation se...

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Detalles Bibliográficos
Autores principales: Rivas, Manuel A., Beaudoin, Melissa, Gardet, Agnes, Stevens, Christine, Sharma, Yashoda, Zhang, Clarence K., Boucher, Gabrielle, Ripke, Stephan, Ellinghaus, David, Burtt, Noel, Fennell, Tim, Kirby, Andrew, Latiano, Anna, Goyette, Philippe, Green, Todd, Halfvarson, Jonas, Haritunians, Talin, Korn, Joshua M., Kuruvilla, Finny, Lagacé, Caroline, Neale, Benjamin, Lo, Ken Sin, Schumm, Phil, Törkvist, Leif, Dubinsky, Marla, Brant, Steven R., Silverberg, Mark, Duerr, Richard H., Altshuler, David, Gabriel, Stacey, Lettre, Guillaume, Franke, Andre, D’Amato, Mauro, McGovern, Dermot P.B., Cho, Judy H., Rioux, John D., Xavier, Ramnik J., Daly, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378381/
https://www.ncbi.nlm.nih.gov/pubmed/21983784
http://dx.doi.org/10.1038/ng.952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378381/
https://www.ncbi.nlm.nih.gov/pubmed/21983784
http://dx.doi.org/10.1038/ng.952

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