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Serial selection for invasiveness increases expression of miR-143/miR-145 in glioblastoma cell lines

BACKGROUND: Glioblastoma multiforme (GBM) is the most common primary central nervous system malignancy and its unique invasiveness renders it difficult to treat. This invasive phenotype, like other cellular processes, may be controlled in part by microRNAs - a class of small non-coding RNAs that act...

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Detalles Bibliográficos
Autores principales: Koo, Sunwoo, Martin, Gail S, Schulz, Kevin J, Ronck, Matthew, Toussaint, L Gerard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378456/
https://www.ncbi.nlm.nih.gov/pubmed/22490015
http://dx.doi.org/10.1186/1471-2407-12-143