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One remarkable molecule: Filaggrin
The discovery, in 2006, that loss-of-function mutations in the filaggrin gene (FLG) are the cause of ichthyosis vulgaris – the most common disorder of keratinization – and also a strong genetic risk factor for atopic eczema, marked a significant breakthrough in the understanding of eczema pathogenes...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378480/ https://www.ncbi.nlm.nih.gov/pubmed/22158554 http://dx.doi.org/10.1038/jid.2011.393 |