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Antigen Delivery to Macrophages Using Liposomal Nanoparticles Targeting Sialoadhesin/CD169

Sialoadhesin (Sn, Siglec-1, CD169) is a member of the sialic acid binding Ig-like lectin (siglec) family expressed on macrophages. Its macrophage specific expression makes it an attractive target for delivering antigens to tissue macrophages via Sn-mediated endocytosis. Here we describe a novel appr...

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Detalles Bibliográficos
Autores principales: Chen, Weihsu C., Kawasaki, Norihito, Nycholat, Corwin M., Han, Shoufa, Pilotte, Julie, Crocker, Paul R., Paulson, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378521/
https://www.ncbi.nlm.nih.gov/pubmed/22723922
http://dx.doi.org/10.1371/journal.pone.0039039