MEK1 Inhibits Cardiac PPARα Activity by Direct Interaction and Prevents Its Nuclear Localization

BACKGROUND: The response of the postnatal heart to growth and stress stimuli includes activation of a network of signal transduction cascades, including the stress activated protein kinases such as p38 mitogen-activated protein kinase (MAPK), c-Jun NH2-terminal kinase (JNK) and the extracellular sig...

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Detalles Bibliográficos
Autores principales: el Azzouzi, Hamid, Leptidis, Stefanos, Bourajjaj, Meriem, van Bilsen, Marc, da Costa Martins, Paula A., De Windt, Leon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378550/
https://www.ncbi.nlm.nih.gov/pubmed/22723831
http://dx.doi.org/10.1371/journal.pone.0036799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378550/
https://www.ncbi.nlm.nih.gov/pubmed/22723831
http://dx.doi.org/10.1371/journal.pone.0036799

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