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Alopecia in a Viable Phospholipase C Delta 1 and Phospholipase C Delta 3 Double Mutant

BACKGROUND: Inositol 1,4,5trisphosphate (IP(3)) and diacylglycerol (DAG) are important intracellular signalling molecules in various tissues. They are generated by the phospholipase C family of enzymes, of which phospholipase C delta (PLCD) forms one class. Studies with functional inactivation of Pl...

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Detalles Bibliográficos
Autores principales: Runkel, Fabian, Hintze, Maik, Griesing, Sebastian, Michels, Marion, Blanck, Birgit, Fukami, Kiyoko, Guénet, Jean-Louis, Franz, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378570/
https://www.ncbi.nlm.nih.gov/pubmed/22723964
http://dx.doi.org/10.1371/journal.pone.0039203