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Echocardiographic Evidence for Valvular Toxicity of Benfluorex: A Double-Blind Randomised Trial in Patients with Type 2 Diabetes Mellitus

OBJECTIVES: REGULATE trial was designed to compare the efficacy and safety of benfluorex versus pioglitazone in type 2 diabetes mellitus (DM) patients. METHODS: Double-blind, parallel-group, international, randomised, non-inferiority trial. More than half of the 196 participating centres were primar...

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Detalles Bibliográficos
Autores principales: Derumeaux, Geneviève, Ernande, Laura, Serusclat, André, Servan, Evelyne, Bruckert, Eric, Rousset, Hugues, Senn, Stephen, Van Gaal, Luc, Picandet, Brigitte, Gavini, François, Moulin, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378581/
https://www.ncbi.nlm.nih.gov/pubmed/22723853
http://dx.doi.org/10.1371/journal.pone.0038273