Increased Membrane Cholesterol in Lymphocytes Diverts T-Cells toward an Inflammatory Response

Cell signaling for T-cell growth, differentiation, and apoptosis is initiated in the cholesterol-rich microdomains of the plasma membrane known as lipid rafts. Herein, we investigated whether enrichment of membrane cholesterol in lipid rafts affects antigen-specific CD4 T-helper cell functions. Enri...

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Detalles Bibliográficos
Autores principales: Surls, Jacqueline, Nazarov-Stoica, Cristina, Kehl, Margaret, Olsen, Cara, Casares, Sofia, Brumeanu, Teodor-D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378591/
https://www.ncbi.nlm.nih.gov/pubmed/22723880
http://dx.doi.org/10.1371/journal.pone.0038733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378591/
https://www.ncbi.nlm.nih.gov/pubmed/22723880
http://dx.doi.org/10.1371/journal.pone.0038733

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