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Increased Membrane Cholesterol in Lymphocytes Diverts T-Cells toward an Inflammatory Response
Cell signaling for T-cell growth, differentiation, and apoptosis is initiated in the cholesterol-rich microdomains of the plasma membrane known as lipid rafts. Herein, we investigated whether enrichment of membrane cholesterol in lipid rafts affects antigen-specific CD4 T-helper cell functions. Enri...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378591/ https://www.ncbi.nlm.nih.gov/pubmed/22723880 http://dx.doi.org/10.1371/journal.pone.0038733 |