IL-25 induces type 2 cytokine production in a novel, steroid resistant IL-17RB(+) myeloid population that exacerbates asthmatic pathology

This study identifies the IL-25 receptor, IL-17RB, is an important mediator of both innate and adaptive pulmonary type 2 immune responses. Allergen exposure upregulated IL-25 and induced type 2 cytokine production in a novel granulocytic population, termed Type 2 Myeloid (T2M) cells. Il17rb(−/−) mic...

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Detalles Bibliográficos
Autores principales: Petersen, Bryan C., Budelsky, Alison L., Baptist, Alan P., Schaller, Matthew A., Lukacs, Nicholas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378776/
https://www.ncbi.nlm.nih.gov/pubmed/22543263
http://dx.doi.org/10.1038/nm.2735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378776/
https://www.ncbi.nlm.nih.gov/pubmed/22543263
http://dx.doi.org/10.1038/nm.2735

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