Neuroimmune semaphorin 4A downregulates the severity of allergic response

To define the role of Sema4A in allergic response, we employed Sema4A(−/−) and WT mice in the experimental model of OVA-induced allergic airway inflammation. We observed a selective increase in eosinophilic airway infiltration accompanied by bronchial epithelial cell hyperplasia in allergen-treated...

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Detalles Bibliográficos
Autores principales: Nkyimbeng-Takwi, EH, Shanks, K, Smith, E, Iyer, A, Lipsky, MM, DeTolla, LJ, Kikutani, H, Keegan, AD, Chapoval, SP
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378810/
https://www.ncbi.nlm.nih.gov/pubmed/22472774
http://dx.doi.org/10.1038/mi.2012.18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378810/
https://www.ncbi.nlm.nih.gov/pubmed/22472774
http://dx.doi.org/10.1038/mi.2012.18

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