Polyadenylation helps regulate functional tRNA levels in Escherichia coli

Here we demonstrate a new regulatory mechanism for tRNA processing in Escherichia coli whereby RNase T and RNase PH, the two primary 3′ → 5′ exonucleases involved in the final step of 3′-end maturation, compete with poly(A) polymerase I (PAP I) for tRNA precursors in wild-type cells. In the absence...

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Detalles Bibliográficos
Autores principales: Mohanty, Bijoy K., Maples, Valerie F., Kushner, Sidney R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378859/
https://www.ncbi.nlm.nih.gov/pubmed/22287637
http://dx.doi.org/10.1093/nar/gks006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378859/
https://www.ncbi.nlm.nih.gov/pubmed/22287637
http://dx.doi.org/10.1093/nar/gks006

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