Evolution and function of CAG/polyglutamine repeats in protein–protein interaction networks

Expanded runs of consecutive trinucleotide CAG repeats encoding polyglutamine (polyQ) stretches are observed in the genes of a large number of patients with different genetic diseases such as Huntington's and several Ataxias. Protein aggregation, which is a key feature of most of these diseases...

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Detalles Bibliográficos
Autores principales: Schaefer, Martin H., Wanker, Erich E., Andrade-Navarro, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378862/
https://www.ncbi.nlm.nih.gov/pubmed/22287626
http://dx.doi.org/10.1093/nar/gks011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378862/
https://www.ncbi.nlm.nih.gov/pubmed/22287626
http://dx.doi.org/10.1093/nar/gks011

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