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Association of the interferon-β gene with pericentromeric heterochromatin is dynamically regulated during virus infection through a YY1-dependent mechanism

Nuclear architecture as well as gene nuclear positioning can modulate gene expression. In this work, we have analyzed the nuclear position of the interferon-β (IFN-β) locus, responsible for the establishment of the innate antiviral response, with respect to pericentromeric heterochromatin (PCH) in c...

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Detalles Bibliográficos
Autores principales: Josse, T., Mokrani-Benhelli, H., Benferhat, R., Shestakova, E., Mansuroglu, Z., Kakanakou, H., Billecocq, A., Bouloy, M., Bonnefoy, Eliette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378888/
https://www.ncbi.nlm.nih.gov/pubmed/22287632
http://dx.doi.org/10.1093/nar/gks050