DNA robustly stimulates FANCD2 monoubiquitylation in the complex with FANCI

FANCI and FANCD2 form a complex, and play essential roles in the repair of interstrand DNA crosslinks (ICLs) by the Fanconi anemia (FA) pathway. FANCD2 is monoubiquitylated by the FA core complex, composed of 10 FA proteins including FANCL as the catalytic E3 subunit. FANCD2 monoubiquitylation can b...

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Detalles Bibliográficos
Autores principales: Sato, Koichi, Toda, Kazue, Ishiai, Masamichi, Takata, Minoru, Kurumizaka, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378891/
https://www.ncbi.nlm.nih.gov/pubmed/22287633
http://dx.doi.org/10.1093/nar/gks053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378891/
https://www.ncbi.nlm.nih.gov/pubmed/22287633
http://dx.doi.org/10.1093/nar/gks053

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