Genome-wide analyses reveal the extent of opportunistic STAT5 binding that does not yield transcriptional activation of neighboring genes

Signal Transducers and Activators of Transcription (STAT) 5A/B regulate cytokine-inducible genes upon binding to GAS motifs. It is not known what percentage of genes with GAS motifs bind to and are regulated by STAT5. Moreover, it is not clear whether genome-wide STAT5 binding is modulated by its co...

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Detalles Bibliográficos
Autores principales: Zhu, Bing-Mei, Kang, Keunsoo, Yu, Ji Hoon, Chen, Weiping, Smith, Harold E., Lee, Daeyoup, Sun, Hong-Wei, Wei, Lai, Hennighausen, Lothar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378893/
https://www.ncbi.nlm.nih.gov/pubmed/22319210
http://dx.doi.org/10.1093/nar/gks056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378893/
https://www.ncbi.nlm.nih.gov/pubmed/22319210
http://dx.doi.org/10.1093/nar/gks056

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