Functional and structural characterization of the mammalian TREX-2 complex that links transcription with nuclear messenger RNA export

Export of messenger RNA (mRNA) from the nucleus to the cytoplasm is a critical step in the gene expression pathway of eukaryotic cells. Here, we report the functional and structural characterization of the mammalian TREX-2 complex and show how it links transcription/processing with nuclear mRNA expo...

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Detalles Bibliográficos
Autores principales: Jani, Divyang, Lutz, Sheila, Hurt, Ed, Laskey, Ronald A., Stewart, Murray, Wickramasinghe, Vihandha O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378895/
https://www.ncbi.nlm.nih.gov/pubmed/22307388
http://dx.doi.org/10.1093/nar/gks059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378895/
https://www.ncbi.nlm.nih.gov/pubmed/22307388
http://dx.doi.org/10.1093/nar/gks059

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