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Genome-wide enhancer prediction from epigenetic signatures using genetic algorithm-optimized support vector machines
The chemical modification of histones at specific DNA regulatory elements is linked to the activation, inactivation and poising of genes. A number of tools exist to predict enhancers from chromatin modification maps, but their practical application is limited because they either (i) consider a small...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378905/ https://www.ncbi.nlm.nih.gov/pubmed/22328731 http://dx.doi.org/10.1093/nar/gks149 |