Oxidative DNA Damage in Neurons: Implication of Ku in Neuronal Homeostasis and Survival

Oxidative DNA damage is produced by reactive oxygen species (ROS) which are generated by exogenous and endogenous sources and continuously challenge the cell. One of the most severe DNA lesions is the double-strand break (DSB), which is mainly repaired by nonhomologous end joining (NHEJ) pathway in...

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Detalles Bibliográficos
Autores principales: De Zio, Daniela, Bordi, Matteo, Cecconi, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378965/
https://www.ncbi.nlm.nih.gov/pubmed/22737170
http://dx.doi.org/10.1155/2012/752420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378965/
https://www.ncbi.nlm.nih.gov/pubmed/22737170
http://dx.doi.org/10.1155/2012/752420

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