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Insulin Rescues Impaired Spermatogenesis via the Hypothalamic-Pituitary-Gonadal Axis in Akita Diabetic Mice and Restores Male Fertility

The mechanism responsible for poor reproductive outcomes in type 1 diabetic males is not well understood. In light of new evidence that the Sertoli cells of the testis secrete insulin, it is currently unclear whether diabetic subfertility is the result of deficiency of pancreatic insulin, testicular...

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Detalles Bibliográficos
Autores principales: Schoeller, Erica L., Albanna, Gabriella, Frolova, Antonina I., Moley, Kelle H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379646/
https://www.ncbi.nlm.nih.gov/pubmed/22522616
http://dx.doi.org/10.2337/db11-1527