ZnT8 Is a Major CD8(+) T Cell–Recognized Autoantigen in Pediatric Type 1 Diabetes

Type 1 diabetes results from the destruction of β-cells by an autoimmune T-cell response assisted by antigen-presenting B cells producing autoantibodies. CD8(+) T-cell responses against islet cell antigens, thought to play a central role in diabetes pathogenesis, can be monitored using enzyme-linked...

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Detalles Bibliográficos
Autores principales: Énée, Émmanuelle, Kratzer, Roland, Arnoux, Jean-Baptiste, Barilleau, Emilie, Hamel, Yamina, Marchi, Christophe, Beltrand, Jacques, Michaud, Bénédicte, Chatenoud, Lucienne, Robert, Jean-Jacques, van Endert, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Immunology and Transplantation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379659/
https://www.ncbi.nlm.nih.gov/pubmed/22586580
http://dx.doi.org/10.2337/db12-0071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379659/
https://www.ncbi.nlm.nih.gov/pubmed/22586580
http://dx.doi.org/10.2337/db12-0071

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