Changes in MicroRNA Expression Contribute to Pancreatic β-Cell Dysfunction in Prediabetic NOD Mice

During the initial phases of type 1 diabetes, pancreatic islets are invaded by immune cells, exposing β-cells to proinflammatory cytokines. This unfavorable environment results in gene expression modifications leading to loss of β-cell functions. To study the contribution of microRNAs (miRNAs) in th...

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Detalles Bibliográficos
Autores principales: Roggli, Elodie, Gattesco, Sonia, Caille, Dorothée, Briet, Claire, Boitard, Christian, Meda, Paolo, Regazzi, Romano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Islet Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379668/
https://www.ncbi.nlm.nih.gov/pubmed/22537941
http://dx.doi.org/10.2337/db11-1086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379668/
https://www.ncbi.nlm.nih.gov/pubmed/22537941
http://dx.doi.org/10.2337/db11-1086

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