Inhibition of Glucose-Stimulated Insulin Secretion by KCNJ15, a Newly Identified Susceptibility Gene for Type 2 Diabetes

Potassium inwardly rectifying channel, subfamily J, member 15 (KCNJ15) is a type 2 diabetes–associated risk gene, and Kcnj15 overexpression suppresses insulin secretion in rat insulinoma (INS1) cells. The aim of the current study was to characterize the role of Kcnj15 by knockdown of this gene in vi...

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Detalles Bibliográficos
Autores principales: Okamoto, Koji, Iwasaki, Naoko, Doi, Kent, Noiri, Eisei, Iwamoto, Yasuhiko, Uchigata, Yasuko, Fujita, Toshiro, Tokunaga, Katsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Islet Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379671/
https://www.ncbi.nlm.nih.gov/pubmed/22566534
http://dx.doi.org/10.2337/db11-1201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379671/
https://www.ncbi.nlm.nih.gov/pubmed/22566534
http://dx.doi.org/10.2337/db11-1201

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