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Investigation of the In Vitro Therapeutic Efficacy of Nilotinib in Immortalized Human NF2-Null Vestibular Schwannoma Cells

Vestibular schwannomas (VS) are a common posterior fossa brain tumor, and though benign can cause significant morbidity, particularly loss of hearing, tinnitus, vertigo and facial paralysis. The current treatment options for VS include microsurgical resection, stereotactic radiosurgery or close surv...

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Detalles Bibliográficos
Autores principales: Sabha, Nesrin, Au, Karolyn, Agnihotri, Sameer, Singh, Sanjay, Mangat, Rupinder, Guha, Abhijit, Zadeh, Gelareh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379978/
https://www.ncbi.nlm.nih.gov/pubmed/22745749
http://dx.doi.org/10.1371/journal.pone.0039412