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Glial Tumor Necrosis Factor Alpha (TNFα) Generates Metaplastic Inhibition of Spinal Learning

Injury-induced overexpression of tumor necrosis factor alpha (TNFα) in the spinal cord can induce chronic neuroinflammation and excitotoxicity that ultimately undermines functional recovery. Here we investigate how TNFα might also act to upset spinal function by modulating spinal plasticity. Using a...

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Detalles Bibliográficos
Autores principales: Huie, J. Russell, Baumbauer, Kyle M., Lee, Kuan H., Bresnahan, Jacqueline C., Beattie, Michael S., Ferguson, Adam R., Grau, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379985/
https://www.ncbi.nlm.nih.gov/pubmed/22745823
http://dx.doi.org/10.1371/journal.pone.0039751