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Wild-Type Phosphoribosylpyrophosphate Synthase (PRS) from Mycobacterium tuberculosis: A Bacterial Class II PRS?

The 5-phospho-α-D-ribose 1-diphosphate (PRPP) metabolite plays essential roles in several biosynthetic pathways, including histidine, tryptophan, nucleotides, and, in mycobacteria, cell wall precursors. PRPP is synthesized from α-D-ribose 5-phosphate (R5P) and ATP by the Mycobacterium tuberculosis p...

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Detalles Bibliográficos
Autores principales: Breda, Ardala, Martinelli, Leonardo K. B., Bizarro, Cristiano V., Rosado, Leonardo A., Borges, Caroline B., Santos, Diógenes S., Basso, Luiz A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380012/
https://www.ncbi.nlm.nih.gov/pubmed/22745722
http://dx.doi.org/10.1371/journal.pone.0039245