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Intracerebroventricular Injection of Encapsulated Human Mesenchymal Cells Producing Glucagon-Like Peptide 1 Prolongs Survival in a Mouse Model of ALS

BACKGROUND: As pharmacological therapies have largely failed so far, stem cell therapy has recently come into the focus of ALS research. Neuroprotective potential was shown for several types of stem and progenitor cells, mainly due to release of trophic factors. In the present study, we assessed the...

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Detalles Bibliográficos
Autores principales: Knippenberg, Sarah, Thau, Nadine, Dengler, Reinhard, Brinker, Thomas, Petri, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380029/
https://www.ncbi.nlm.nih.gov/pubmed/22745655
http://dx.doi.org/10.1371/journal.pone.0036857