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Intracerebroventricular Injection of Encapsulated Human Mesenchymal Cells Producing Glucagon-Like Peptide 1 Prolongs Survival in a Mouse Model of ALS
BACKGROUND: As pharmacological therapies have largely failed so far, stem cell therapy has recently come into the focus of ALS research. Neuroprotective potential was shown for several types of stem and progenitor cells, mainly due to release of trophic factors. In the present study, we assessed the...
Autores principales: | Knippenberg, Sarah, Thau, Nadine, Dengler, Reinhard, Brinker, Thomas, Petri, Susanne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380029/ https://www.ncbi.nlm.nih.gov/pubmed/22745655 http://dx.doi.org/10.1371/journal.pone.0036857 |
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