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Troglitazone Attenuates TGF-β1-Induced EMT in Alveolar Epithelial Cells via a PPARγ-Independent Mechanism

Peroxisome proliferator activated receptor γ (PPARγ) agonists are effective antifibrotic agents in a number of tissues. Effects of these agents on epithelial-mesenchymal transition (EMT) of primary alveolar epithelial cells (AEC) and potential mechanisms underlying effects on EMT have not been well...

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Detalles Bibliográficos
Autores principales: Zhou, Beiyun, Buckley, Stephen T., Patel, Vipul, Liu, Yixin, Luo, Jiao, Krishnaveni, Manda Sai, Ivan, Mihaela, DeMaio, Lucas, Kim, Kwang-Jin, Ehrhardt, Carsten, Crandall, Edward D., Borok, Zea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380041/
https://www.ncbi.nlm.nih.gov/pubmed/22745681
http://dx.doi.org/10.1371/journal.pone.0038827