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Insulin Concentration Modulates Hepatic Lipid Accumulation in Mice in Part via Transcriptional Regulation of Fatty Acid Transport Proteins

BACKGROUND: Fatty liver disease (FLD) is commonly associated with insulin resistance and obesity, but interestingly it is also observed at low insulin states, such as prolonged fasting. Thus, we asked whether insulin is an independent modulator of hepatic lipid accumulation. METHODS/PRINCIPAL FINDIN...

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Detalles Bibliográficos
Autores principales: Softic, Samir, Kirby, Michelle, Berger, Nicholas G., Shroyer, Noah F., Woods, Stephen C., Kohli, Rohit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380053/
https://www.ncbi.nlm.nih.gov/pubmed/22745692
http://dx.doi.org/10.1371/journal.pone.0038952