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Insulin Concentration Modulates Hepatic Lipid Accumulation in Mice in Part via Transcriptional Regulation of Fatty Acid Transport Proteins
BACKGROUND: Fatty liver disease (FLD) is commonly associated with insulin resistance and obesity, but interestingly it is also observed at low insulin states, such as prolonged fasting. Thus, we asked whether insulin is an independent modulator of hepatic lipid accumulation. METHODS/PRINCIPAL FINDIN...
Autores principales: | Softic, Samir, Kirby, Michelle, Berger, Nicholas G., Shroyer, Noah F., Woods, Stephen C., Kohli, Rohit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380053/ https://www.ncbi.nlm.nih.gov/pubmed/22745692 http://dx.doi.org/10.1371/journal.pone.0038952 |
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