Cargando…
Transforming growth factor-β signaling to T cells inhibits autoimmunity during lymphopenia-driven proliferation
T cell specific deletion of the Transforming growth factor-β (TGF-β) receptor mediated by CD4-cre leads to early onset lethal autoimmune disease that cannot be controlled by regulatory T cells. However, when we delete the receptor using distal Lck (dLck) promoter driven cre, adult mice in which the...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380154/ https://www.ncbi.nlm.nih.gov/pubmed/22634866 http://dx.doi.org/10.1038/ni.2319 |