Cargando…

CYP4A11 variant is associated with high density lipoprotein cholesterol in women

The ω-hydroxylase CYP4A11 catalyzes the transformation of epoxyeicosatrienoic acids to omega-hydroxylated-epoxyeicosatrienoic acids, endogenous peroxisome proliferator-activated receptor α (PPARα) agonists. PPARα activation increases high-density lipoprotein-cholesterol (HDL-C). A cytosine-for-thymi...

Descripción completa

Detalles Bibliográficos
Autores principales: White, Charles C., Feng, QiPing, Cupples, L. Adrienne, Gainer, James V., Dawson, Elliott P., Wilke, Russell A., Brown, Nancy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380161/
https://www.ncbi.nlm.nih.gov/pubmed/21912424
http://dx.doi.org/10.1038/tpj.2011.40