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B-cell numbers and phenotype at clinical relapse following rituximab therapy differ in SLE patients according to anti-dsDNA antibody levels

Objectives. To correlate the kinetics of B-cell repopulation with relapse after B-cell depletion therapy in SLE patients and address whether variation in relapse rate, B-cell numbers and phenotype are related to anti-dsDNA antibody levels. Methods. Sixty-one patients with refractory SLE were treated...

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Detalles Bibliográficos
Autores principales: Lazarus, Mark N., Turner-Stokes, Tabitha, Chavele, Konstantia-Maria, Isenberg, David A., Ehrenstein, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380246/
https://www.ncbi.nlm.nih.gov/pubmed/22337941
http://dx.doi.org/10.1093/rheumatology/ker526