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Regulation of CD8(+) T Cell Responses to Retinal Antigen by Local FoxP3(+) Regulatory T Cells

While pathogenic CD4 T cells are well known mediators of autoimmune uveoretinitis, CD8 T cells can also be uveitogenic. Since preliminary studies indicated that C57BL/6 mice were minimally susceptible to autoimmune uveoretinitis induction by CD8 T cells, the basis of the retinal disease resistance w...

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Detalles Bibliográficos
Autores principales: McPherson, Scott W., Heuss, Neal D., Gregerson, Dale S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380377/
https://www.ncbi.nlm.nih.gov/pubmed/22737153
http://dx.doi.org/10.3389/fimmu.2012.00166