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Cardiac-specific deletion of the microtubule-binding protein CENP-F causes dilated cardiomyopathy

CENP-F is a large multifunctional protein with demonstrated regulatory roles in cell proliferation, vesicular transport and cell shape through its association with the microtubule (MT) network. Until now, analysis of CENP-F has been limited to in vitro analysis. Here, using a Cre-loxP system, we rep...

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Detalles Bibliográficos
Autores principales: Dees, Ellen, Miller, Paul M., Moynihan, Katherine L., Pooley, Ryan D., Hunt, R. Pierre, Galindo, Cristi L., Rottman, Jeffrey N., Bader, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380710/
https://www.ncbi.nlm.nih.gov/pubmed/22563055
http://dx.doi.org/10.1242/dmm.008680