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Cardiac-specific deletion of the microtubule-binding protein CENP-F causes dilated cardiomyopathy
CENP-F is a large multifunctional protein with demonstrated regulatory roles in cell proliferation, vesicular transport and cell shape through its association with the microtubule (MT) network. Until now, analysis of CENP-F has been limited to in vitro analysis. Here, using a Cre-loxP system, we rep...
Autores principales: | Dees, Ellen, Miller, Paul M., Moynihan, Katherine L., Pooley, Ryan D., Hunt, R. Pierre, Galindo, Cristi L., Rottman, Jeffrey N., Bader, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Limited
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380710/ https://www.ncbi.nlm.nih.gov/pubmed/22563055 http://dx.doi.org/10.1242/dmm.008680 |
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