Paneth cell ablation in the presence of Klebsiella pneumoniae induces necrotizing enterocolitis (NEC)-like injury in the small intestine of immature mice

Necrotizing enterocolitis (NEC) is a leading cause of morbidity and mortality in premature infants. During NEC pathogenesis, bacteria are able to penetrate innate immune defenses and invade the intestinal epithelial layer, causing subsequent inflammation and tissue necrosis. Normally, Paneth cells a...

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Detalles Bibliográficos
Autores principales: Zhang, Chunxian, Sherman, Michael P., Prince, Lawrence S., Bader, David, Weitkamp, Jörn-Hendrik, Slaughter, James C., McElroy, Steven J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380715/
https://www.ncbi.nlm.nih.gov/pubmed/22328592
http://dx.doi.org/10.1242/dmm.009001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380715/
https://www.ncbi.nlm.nih.gov/pubmed/22328592
http://dx.doi.org/10.1242/dmm.009001

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