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Quantitative changes in intracellular calcium and extracellular-regulated kinase activation measured in parallel in CHO cells stably expressing serotonin (5-HT) 5-HT(2A )or 5-HT(2C )receptors

BACKGROUND: The serotonin (5-HT) 2A and 2C receptors (5-HT(2A)R and 5-HT(2C)R) are involved in a wide range of physiological and behavioral processes in the mammalian central and peripheral nervous systems. These receptors share a high degree of homology, have overlapping pharmacological profiles, a...

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Detalles Bibliográficos
Autores principales: Seitz, Patricia K, Bremer, Nicole M, McGinnis, Andrew G, Cunningham, Kathryn A, Watson, Cheryl S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380724/
https://www.ncbi.nlm.nih.gov/pubmed/22397586
http://dx.doi.org/10.1186/1471-2202-13-25