Rare Copy Number Variants Observed in Hereditary Breast Cancer Cases Disrupt Genes in Estrogen Signaling and TP53 Tumor Suppression Network

Breast cancer is the most common cancer in women in developed countries, and the contribution of genetic susceptibility to breast cancer development has been well-recognized. However, a great proportion of these hereditary predisposing factors still remain unidentified. To examine the contribution o...

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Detalles Bibliográficos
Autores principales: Pylkäs, Katri, Vuorela, Mikko, Otsukka, Meeri, Kallioniemi, Anne, Jukkola-Vuorinen, Arja, Winqvist, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380845/
https://www.ncbi.nlm.nih.gov/pubmed/22737080
http://dx.doi.org/10.1371/journal.pgen.1002734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380845/
https://www.ncbi.nlm.nih.gov/pubmed/22737080
http://dx.doi.org/10.1371/journal.pgen.1002734

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