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Fragile Mental Retardation Protein Interacts with the RNA-Binding Protein Caprin1 in Neuronal RiboNucleoProtein Complexes

Fragile X syndrome is caused by the absence of the Fragile X Mental Retardation Protein (FMRP), an RNA-binding protein. FMRP is associated with messenger RiboNucleoParticles (mRNPs) present in polyribosomes and its absence in neurons leads to alteration in synaptic plasticity as a result of translat...

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Detalles Bibliográficos
Autores principales: El Fatimy, Rachid, Tremblay, Sandra, Dury, Alain Y., Solomon, Samuel, De Koninck, Paul, Schrader, John W., Khandjian, Edouard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380850/
https://www.ncbi.nlm.nih.gov/pubmed/22737234
http://dx.doi.org/10.1371/journal.pone.0039338