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Actin Polymerization Controls the Organization of WASH Domains at the Surface of Endosomes

Sorting of cargoes in endosomes occurs through their selective enrichment into sorting platforms, where transport intermediates are generated. The WASH complex, which directly binds to lipids, activates the Arp2/3 complex and hence actin polymerization onto such sorting platforms. Here, we analyzed...

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Detalles Bibliográficos
Autores principales: Derivery, Emmanuel, Helfer, Emmanuèle, Henriot, Véronique, Gautreau, Alexis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380866/
https://www.ncbi.nlm.nih.gov/pubmed/22737254
http://dx.doi.org/10.1371/journal.pone.0039774