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Actin Polymerization Controls the Organization of WASH Domains at the Surface of Endosomes
Sorting of cargoes in endosomes occurs through their selective enrichment into sorting platforms, where transport intermediates are generated. The WASH complex, which directly binds to lipids, activates the Arp2/3 complex and hence actin polymerization onto such sorting platforms. Here, we analyzed...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380866/ https://www.ncbi.nlm.nih.gov/pubmed/22737254 http://dx.doi.org/10.1371/journal.pone.0039774 |