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Modelling Cell Polarization Driven by Synthetic Spatially Graded Rac Activation
The small GTPase Rac is known to be an important regulator of cell polarization, cytoskeletal reorganization, and motility of mammalian cells. In recent microfluidic experiments, HeLa cells endowed with appropriate constructs were subjected to gradients of the small molecule rapamycin leading to syn...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380869/ https://www.ncbi.nlm.nih.gov/pubmed/22737059 http://dx.doi.org/10.1371/journal.pcbi.1002366 |