Changes in Global Gene Expression Associated with 3D Structure of Tumors: An Ex Vivo Matrix-Free Mesothelioma Spheroid Model

Tumor microenvironments present significant barriers to anti-tumor agents. Molecules involved in multicellular tumor microenvironments, however, are difficult to study ex vivo. Here, we generated a matrix-free tumor spheroid model using the NCI-H226 mesothelioma cell line and compared the gene expre...

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Detalles Bibliográficos
Autores principales: Kim, Heungnam, Phung, Yen, Ho, Mitchell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380922/
https://www.ncbi.nlm.nih.gov/pubmed/22737246
http://dx.doi.org/10.1371/journal.pone.0039556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380922/
https://www.ncbi.nlm.nih.gov/pubmed/22737246
http://dx.doi.org/10.1371/journal.pone.0039556

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