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Age related changes in microglial phenotype vary between CNS regions: Grey versus white matter differences

Subtle regional differences in microglial phenotype exist in the adult mouse brain. We investigated whether these differences were amplified during ageing and following systemic challenge with lipopolysaccharide (LPS). We studied microglial morphology and phenotype in young (4mo) and aged (21mo) C57...

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Detalles Bibliográficos
Autores principales: Hart, Adam D., Wyttenbach, Andreas, Hugh Perry, V., Teeling, Jessica L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381227/
https://www.ncbi.nlm.nih.gov/pubmed/22155499
http://dx.doi.org/10.1016/j.bbi.2011.11.006