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Role of host-encoded proteins in restriction of retroviral integration

In retroviral infections, a copy of the viral DNA is first synthesized from genomic RNA by reverse transcription and subsequently integrated into host chromatin. This integration step, executed by the viral enzyme integrase (IN), is one of the hallmarks of retroviral infection. Although an obligate...

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Detalles Bibliográficos
Autores principales: Suzuki, Yasutsugu, Chew, Mun Lok, Suzuki, Youichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381236/
https://www.ncbi.nlm.nih.gov/pubmed/22737148
http://dx.doi.org/10.3389/fmicb.2012.00227