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Mouse Models of SCN5A-Related Cardiac Arrhythmias

Mutations of SCN5A gene, which encodes the α-subunit of the voltage-gated Na(+) channel Na(V)1.5, underlie hereditary cardiac arrhythmic syndromes such as the type 3 long QT syndrome, cardiac conduction diseases, the Brugada syndrome, the sick sinus syndrome, a trial standstill, and numerous overlap...

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Detalles Bibliográficos
Autores principales: Derangeon, Mickael, Montnach, Jérôme, Baró, Isabelle, Charpentier, Flavien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381239/
https://www.ncbi.nlm.nih.gov/pubmed/22737129
http://dx.doi.org/10.3389/fphys.2012.00210