Protected Graft Copolymer (PGC) in Imaging and Therapy: A Platform for the Delivery of Covalently and Non-Covalently Bound Drugs

Initially developed in 1992 as an MR imaging agent, the family of protected graft copolymers (PGC) is based on a conjugate of polylysine backbone to which methoxypoly(ethylene glycol) (MPEG) chains are covalently linked in a random fasion via N-ε-amino groups. While PGC is relatively simple in terms...

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Detalles Bibliográficos
Autores principales: Bogdanov Jr, Alexei A., Mazzanti, Mary, Castillo, Gerardo, Bolotin, Elijah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381344/
https://www.ncbi.nlm.nih.gov/pubmed/22737192
http://dx.doi.org/10.7150/thno.4070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381344/
https://www.ncbi.nlm.nih.gov/pubmed/22737192
http://dx.doi.org/10.7150/thno.4070

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